Herpesvirus type 2-induced thymidine kinase and carcinoma of the cervix.

PCR detection of thymidine kinase gen of latent herpes simplex Virus type 1 in mice trigeminal ganglia

  Herpes simplex virus type 1 establishes a latent infection in the peripheral nervous system following primary infection. During latent infection, virus genome exhibit limited transcription, with the HSV LATs consistently detected in latency infected ganaglia. Following ocular infection viral latency develops in the trigeminal ganglia. In this study PCR has been used for detection of HSV-1 nuc...

The Relationship between Herpes Virus 2 and Cervical Cancer

The cpi<lemiologic features of carcinoma cf the cervix indicate that environmental factors play a role in the occurrence cf the disease. The d:sease occurs more frequently in women who have multiple sex pari:ners, consort with uncircumcised men and who begin heterosexual activity early in life. These demographic fea­tures have led to the hypothe.s'"s that the cfo:-ease may be causeJ. by a vener...

Restriction Enzyme Analysis of Thymidine Kinase Gene in Four Iranian Isolates of Herpes Simplex Virus Type 1

Detection of infectious laryngotracheitis virus (Gallid herpesvirus-1) from clinically infected chickens in Egypt by different diagnostic methods

Infectious laryngotracheitis (ILT) disease is an acute highly contagious viral disease leading to massive economic losses to the national poultry industry. This study aimed to identify the most accurate and rapid diagnostic methods to rescue layer poultry farms from intense outbreaks in Egypt. Fifty pathological specimens were collected and subjected to virus isolation (VI), histopathology, dir...

Utility of P16/INK4a and Ki-67 in Preneoplasticand Neoplastic Lesions of Cervix

Background and Objective: The currentstudy aimed at investigating the histomorphological spectrum of cervical intraepithelial and invasive lesions assessing the diagnostic significance of P16/INK4a and Ki-67 in such lesions, andcorrelatingP16/INK4a and Ki-67 immunoexpression with histologic type and grade.Methods: A total of 60 cases were selectedcomprisi...